O-5 Novel HLA II associations in myasthenia gravis
نویسندگان
چکیده
O-3 Clinical features and outcome measures during 1 year enzyme replacement therapy in late onset GSD II patients C. Angelini, C. Semplicini, E. Pegoraro, M. Filosto, G. Marrosu R. Piras, T. Mongini, L. Vercelli, P. Tonin, S. Servidei, R. Di Giacopo, G. Crescimanno, S. Ravaglia, A. Toscano, O. Musumeci, G. Siciliano, G. Ricci, Di Iorio, F. Cipullo, M. Moggio, G. Comi, V. Lucchini, L. Morandi 1 University of Padova, Department of Neurosciences, Padova, Italy; 2 Hospital of Brescia, Italy; 3 University of Cagliari, Italy; 4 University of Torino, Centre for Neuromuscular Diseases, Department of Neurosciences, Torino, Italy; 5 University of Verona; 6 Catholic University of Rome, Italy; 7 University of Palermo, Italy; 8 University of Pavia, Italy; 9 Department of Neurosciences, Psichiatry and Anesthesiology, University of Messina, Italy; 10 University of Pisa, Italy; 11 Second University of Napoli; 12 Deparment of Neurological Sciences, University of Milan, Italy; 13 Besta Institute, Milan, Italy
منابع مشابه
Association of HLA-DQA1*0101/2 and DQB1*0502 with Myasthenia Gravis in Southern Iranian Patients
Background: Myasthenia gravis is an autoimmune disorder of neuromuscular junction characterized by skeletal muscle weakness and fatigability. Different genes may control the induction and clinical presentation of this disease. Various HLA alleles are reported as predisposing or protective genetic elements in myasthenia gravis. Objective: The aim of this study was to investigate the probable as...
متن کاملAssociation between myasthenia gravis and HLA antigens in patients
Introduction: Myasthenia gravis is a disease of neuromuscular junction. Familial cases have been reported. Relation between myasthenia gravis and HLA antigens has been seen in many studies from different parts of the world. The aim of this study is determination of association between HLA class I haplotypes and myasthenia gravis in Kerman province. Methods: In this cross sectional study 44 my...
متن کاملHLA-DRBI ALLELE FREQUENCY IN MYAS THENIA GRAVIS PATIENTS FROM SOUTHERN IRAN
HLA-DRB1 allele frequencies of 28 myasthenia gravis (MG) patients, residents of southern Iranian provinces, were studied using PCR-SSP method. The control group consisted of 100 healthy individuals of the same ethnic group. The allele HLA-DRB1 * 16 (RR= 2.04, p= 0.028) was found to be significantly increased in MG patients compared to the control group, whereas HLADRB1 * 15(RR= 0.17 p= 0.0...
متن کاملAssociation of HLA-DQA1*0101/2 and DQB1*0502 with myasthenia gravis in southern Iranian patients.
BACKGROUND Myasthenia gravis is an autoimmune disorder of neuromuscular junction characterized by skeletal muscle weakness and fatigability. Different genes may control the induction and clinical presentation of this disease. Various HLA alleles are reported as predisposing or protective genetic elements in myasthenia gravis. OBJECTIVE The aim of this study was to investigate the probable ass...
متن کاملImmune disease and HLA associations with myasthenia gravis.
In the late 1950's laboratory and clinical evidence suggested that myasthenia gravis was an autoimmune disorder. Since then a voluminous literature has developed documenting the many immunological abnormalities that occur in this condition. Recent findings point to a central disorder of immunoregulation. It is postulated that the disease occurs as a result of host genetic and environmental infl...
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عنوان ژورنال:
دوره 30 شماره
صفحات -
تاریخ انتشار 2011